TECHNOLOGY USE AMONG INDIGENOUS ADOLESCENTS IN REMOTE REGIONS OF AUSTRALIA




Power and sample sizes estimation in clinical trials with treatment switching in intention-to-treat analysis: a simulation study

Abstract Background Treatment switching, also called crossover, is common in clinical trials because of ethical concerns or other reasons.When it occurs and the primary objective is to identify treatment effects, the most widely used intention-to-treat analysis may lead to underpowered trials.Here, we presented an approach to preview power reductio

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